Letter: Prof Christopher Smith of UK Research and Innovation responds to an article on grants being lost post-Brexit, and offers some reassurance.
Details are published [Thanks to Brexit, I lost a €2.5m research grant. I did want to take this opportunity, though, to reassure researchers who have been successful in the first and second wave of Horizon Europe calls that guaranteed funding is available through UK Research and Innovation (UKRI).
Water sustainability is one of the main missions of Sustainable Carolina, UNC's campus-wide organization dedicated to reducing environmental footprint.
“But we decided that in the water plan, we wanted to keep raising aspirations for water reuse, for water efficiency. And we have, I think, continued to do that in this plan, and done it in a really nice, collaborative manner.” “Connecting to research is a big goal for us in Sustainable Carolina,” said Piehler. As UNC grew into the University that it is today, the water and sewer systems have also expanded. “Water is a necessary, important resource,” Margaret Holton, Water Resources Manager for UNC Energy Services, said in an email statement. The organization's new water plan has prioritized reducing consumption and amplifying research.
FSU researcher Eric Coleman urges restoration efforts to be built upon the communities most affected by conservation endeavors.
“In some organized communities, the people collaborate with governments,” he said. Coleman identified the major problem of global policy efforts as lands that are prioritized for restoration becoming heavily concentrated in the tropics. The benefits that yield from this area has declined in the surrounding local communities. Florida State professor Eric Coleman has conducted research indicating the key to successful land restoration is heavily impacted by the occupants of said space. “Community involvement means that local people need to have a voice in these decisions from the beginning to the end.They help plan restoration activities, select the species they want planted and monitor the land so that people aren’t harvesting before they should.” He credits dipping his toes into this theory due to stories from India,
The consequences of aged ovaries extend beyond fertility, especially during menopause, the period of time when a person stops having a menstrual cycle.
We don't know the answer to that," she said. With the help of investors, Garrison has launched the Global Consortium for Reproductive Longevity and Equality. "But understanding what causes it and figuring out interventions that would extend it a little bit by one year, two years, five years, 10 years -- that is very achievable." The average age of natural menopause in the United States is 51, according to the North American Menopause Society. In 2020, the NIH issued its first research grant on sex and gender, calling it a "milestone achievement." In 2017, the National Institutes of Health issued an amendment to its policies on enrolling women and minorities in clinical trials -- the new language mandates study results are reported by sex/gender and race/ethnicity. "That would be a completely irresponsible goal and ultimately a shortsighted one. "Studies show women who have later menopause tend to live longer and have an enhanced ability to repair their DNA," Garrison said. By the time your mother was born, however, her infantile ovaries only carried 1 million to 2 million eggs, according to the American College of Obstetricians and Gynecologists. We can think about them like an accelerated model for human aging," said Jennifer Garrison, an assistant professor at California's Buck Institute for Research on Aging, the world's first biomedical research institution devoted exclusively to the science of aging. The age of menopause is also tied to longevity. "Even in healthy women, it dramatically increases the risk of stroke, heart disease, cognitive decline, insomnia, osteoporosis, weight gain, arthritis -- those are medically established facts."
(CNN) – Lengthening a woman's fertility may extend her life as well. Research shows women who have later menopause tend to live longer. Ovaries age twice as ...
However, there is still little data about why women go through menopause at all. The center is researching the underlying causes of accelerated aging in the ovaries. With the help of investors, there is now a
The consequences of aged ovaries extend beyond fertility, especially during menopause, the period of time when a person stops having a menstrual cycle.
We don't know the answer to that," she said. With the help of investors, Garrison has launched the Global Consortium for Reproductive Longevity and Equality. "But understanding what causes it and figuring out interventions that would extend it a little bit by one year, two years, five years, 10 years -- that is very achievable." The average age of natural menopause in the United States is 51, according to the North American Menopause Society. In 2020, the NIH issued its first research grant on sex and gender, calling it a "milestone achievement." In 2017, the National Institutes of Health issued an amendment to its policies on enrolling women and minorities in clinical trials -- the new language mandates study results are reported by sex/gender and race/ethnicity. "That would be a completely irresponsible goal and ultimately a shortsighted one. "Studies show women who have later menopause tend to live longer and have an enhanced ability to repair their DNA," Garrison said. By the time your mother was born, however, her infantile ovaries only carried 1 million to 2 million eggs, according to the American College of Obstetricians and Gynecologists. We can think about them like an accelerated model for human aging," said Jennifer Garrison, an assistant professor at California's Buck Institute for Research on Aging, the world's first biomedical research institution devoted exclusively to the science of aging. The age of menopause is also tied to longevity. "Even in healthy women, it dramatically increases the risk of stroke, heart disease, cognitive decline, insomnia, osteoporosis, weight gain, arthritis -- those are medically established facts."
The combination of pembrolizumab, an immunotherapy drug, and guadecitabine, a next-generation DNA hypomethylating agent, halted the advance of cancer in more ...
“I hope this new experimental drug combination will eventually make it to the clinic and help people who have developed resistance to pembrolizumab.” The results are published in the Journal for ImmunoTherapy of This combination might be a way to target their cancer even after it has stopped responding to immunotherapy.” The study used pembrolizumab and guadecitabine to treat 34 cancer patients, 30 of whom had their tumours analysed for immune activity and cancer growth. Three-fifths of the group (60%) were resistant to immunotherapy before the trial. However, it cannot help all patients, and some tumours can evolve to resist it.
New social and public housing research into the High-Risk Accommodation Response program offers unabashed insight into the situations many Victorians found ...
“The Department of Families, Fairness and Housing asked us to listen to the voices of the residents living in high-risk accommodation settings during the pandemic. The report makes recommendations for actions on how governments and health services need to respond, and what can be done to understand and support people living in public housing settings who may experience overwhelming challenges. A key finding of the research is that local community health services are critical for successful communication and engagement in these settings. The project has had immediate impact on many residents through enabling frontline workers to better understand the needs of the residents, assess whether services were meeting their requirements and realign services and delivery while operating within a major public health emergency. The study also worked with frontline community health workers to uncover what they did to understand residents’ requirements and assist them. The voices of more than 800 residents reveal the challenges, their fears, and the strength and resilience that helped many residents prevail, despite significant adversities.
Just two years after graduating from Azusa Pacific, Hannah Valencia '20 is already applying the knowledge and hands-on training acquired through her biology ...
She plans to complete a PhD in Virology, aspiring to continue in the research profession, and she desires to work alongside and mentor others as they delve into the unknowns of science, creating new knowledge. “Her advocacy for using science to better understand and care for the environment is a perfect demonstration of how she uses her career and her faith to prompt change. “She encouraged me to attend seminars hosted by APU and taught me how faith is intrinsically connected to our call to be good stewards of the environment,” Valencia said. Richart’s research focuses on the analysis of a fungus, Aspergillus sclerotiorum, that is pathogenic to termites, meaning the discovery of a natural pesticide. This unique experience enables students to direct the development of a research project under the mentorship of a faculty member. The accomplished young scientist credits her success to the skills she cultivated as an undergraduate researcher at APU under the mentorship of [Sarah Richart, PhD](/faculty/srichart/), professor in the [Department of Biology and Chemistry](/clas/biochem/).
New research exploring the impact of stigma on fuelling inequalities experienced by UK disabled adults in later life has secured funding of £2m.
Furthermore, older disabled adults are under-represented and often excluded from the practical processes that support them. The project will launch in September 2022, with the final report expected in 2027. The project will also build an ‘Inclusive Living Alliance’ – a UK wide network made up of organisations from housing, health, social care and the third sector – to road test this guidance and focus on long-term policy change.
Solving example problems is only the first step in mathematical research. The most important part, the part that allows researchers to establish mathematic.
“You’re always going to have questions, and after you ask one question, you’re going to think of 17 more. Though the research studied bond lattices in a purely mathematical sense, the findings could help inform why they are important and how and where they form in nature. And at some point, you’ll find an answer that makes sense.” “There are these mathematical properties about the networks that translate really well to biological properties,” Gutierrez said. “But in the first lecture, I heard this voice I recognized from my math classes, and it was a major relief. “I was terrified going into the conference because I thought I’d be spending the week by myself,” Rubenfeld said.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19) pandemic, is an enveloped, positive- ...
The study highlights the potency of cetylpyridinium chloride in inhibiting SARS-CoV-2 and its variants even at low concentrations. The mouthwash exhibits similar or even better antiviral efficacy than pure cetylpyridinium chloride solution. The spherical particle structure of SARS-CoV-2 remained unchanged after cetylpyridinium chloride treatment. Saliva samples collected from healthy donors were mixed with the virus and cetylpyridinium chloride to determine the antiviral efficacy of the compound in saliva. These findings indicate that cetylpyridinium chloride reduces the amount of infectious virus before host cell entry. The plaque assay was conducted to examine viral infectivity in the presence and absence of the compound.
I was already glum about soon turning 40. Then I learned that happiness is u-shaped – it bottoms out in your 40s, then starts to inch its way up again in ...
Had I partaken in the survey last year, I would have wanted to clarify that with a newborn in the house, my husband’s Apple watch sleep tracker looked like a seismograph at the base of Vesuvius in AD79. “The U-Shape pattern in mid-life even extends beyond humans to apes,” the researchers write, conjuring King Kong on a chaise longue. “You’re just able to weather the shocks better, even if it isn’t a perfect landing.” Suffice it to say, I’m not sure I need a national survey to illuminate my diminishing leisure time, and the depressing ways I choose to spend it. “Millennials got hit hard in so many different ways,” Carol Graham, an expert in the field of economics and happiness, told me. She’s the author of several books including Happiness around the World: the Paradox of Happy Peasants and Miserable Millionaires. (Duh.) Sure, according to the study we’re also investing more time in “personal care activities”, a bucket which largely includes sleeping but also “grooming”, though I’ll be the first to admit that I no longer have to expend any time filing my nails because they are basically nubbins (thank you, anxiety!). No, I think whenever I’m forced to confront my reality as an almost-middle-ager, I am still 22 and my silky, lacy undergarments would be more at home on a Victoria’s Secret billboard than in Ma’s closet on the prairie. Would I really have to wait until my mid-50s to relax and think? The study by the US Census Bureau and Bureau of Labor Statistics measures how people spend their days – working, exercising, housekeeping, eating and the like. But probably some of this increase is due to self-help that we have been forced to administer, post-pandemic, and, regardless, can the Census Bureau accurately capture the nuances of what “sleeping” looks like with three children under the age of six and a half? This is a remarkably consistent finding, across countries and cultures.
Millions of years on. modern frogs and toads still haven't learnt you can have too much of a good thing.
[trees](https://www.nwf.org/Educational-Resources/Wildlife-Guide/Amphibians/Tree-Frogs), [in flowers](https://naturebackin.com/2017/02/16/against-the-odds-finding-tree-frogs-in-flowers/), in the jungle and [in the desert](https://museum.wa.gov.au/explore/articles/meet-frogs-live-desert). [2019 UN report](https://ipbes.net/) showed amphibians, particularly frogs, are [among the hardest hit](https://www.businessinsider.com/frogs-amphibians-dying-6th-mass-extinction-photos-2019-6?r=US&IR=T) by the nature crisis. But they are [vulnerable to disease](https://www.theguardian.com/environment/2021/jun/16/disease-causing-mass-deaths-frogs-reaches-britain-aoe), which can be [driven by human impacts on nature](https://www.science.org/doi/full/10.1126/science.aav0379). It is an incredible time capsule of over 50,000 fossils from a former lignite (brown coal) opencast mine in the Geiseltal. They mated with numerous other toads during the very short mating season which, in some [modern tropical species](https://bmcecol.biomedcentral.com/articles/10.1186/s12898-019-0243-y), lasts for just hours. The carcasses were moved by light currents in the swampy lakes and sank to the bottom in the cold, deep, and undisturbed regions of the lake. That’s information the frogs took to the grave with them as these three causes of death are difficult to verify. It explains why similar mass graves have been found in different parts of the world. It’s incredible to think these little creatures [survived the dinosaurs’ extinction.](https://choice.npr.org/index.html?origin=https://www.npr.org/sections/thetwo-way/2017/07/03/535383841/how-frogs-benefited-from-the-dinosaurs-extinction#:%7E:text=But%20scientists%20say%20they've,vacuum%20other%20animals%20left%20behind) But a lower level mass death did take place in what is now called the Geiseltal region in central Germany and the cause has long remained a mystery. But my team’s [study](https://doi.org/10.1002/spp2.1453) found an explanation: they died from exhaustion while mating. We also found evidence the frog carcasses floated in the water for some time before they sank to the lake bottom. With this data we were able to reveal what happened to the frog skeletons after their death and to interpret the reason for their death.
Lab services manager Cathy Booth and computing support analyst Brian Palermo will be honored with the 2021 Marsh O'Neill Award for Exceptional and Enduring ...
- George Triantis, senior associate vice provost for research and the Charles J. I find that being able to support that kind of research is important.” “But I didn’t expect to actually get it, and so when I did, I was very excited.” “The Chemistry Department is a giant computer system with some solvent cabinets, fume hoods, and lasers attached,” Fayer wrote in a nomination letter. Palermo manages hundreds of computers in the Chemistry Department, which includes specialized computer needs for a wide range of chemists. Palermo was excited to learn he received the award. “Through the years, Cathy supported the department’s researchers and facilities with her savvy poise and dedication.” As I was there longer and longer, I just knew things, and that was very enjoyable. “I happened to work where somebody will stop and let you know how much they appreciate you,” Booth said. The team I worked with is amazing, and it just makes the whole department right.” Hansen Laboratories from 1952 until 1990, and the first recipient of the award. More than two dozen faculty members nominated 14 staff for the award this year.
SCI Researcher Nafhesa Ali is the co-author of a newly published journal article about the benefits and risks associated with working with community ...
NOAA Administrator Rick Spinrad said in a statement over the next five years that $3.3 billion will support Americans to prepare and adapt for any weather ...
Researchers say the technology could one day be used at home, and enhance memory function in people at risk for dementia. Image: Reinhart Lab.
Some people experienced a slight “poking sensation” on their scalp, he said, but they generally found the sensation very manageable. “If someone is above the age of 65 and their No. “You can imagine a future potentially where people are using stimulation,” he said. Overall, he acknowledged, that previous research on the topic has been a mixed bag. The study also found that the intervention was capable of boosting both working memory and long-term memory. Worrell, of the Mayo Clinic, Forty people in the study received a placebo treatment — they wore the cap but didn't receive the electrical stimulation. The study found that memory performance improved by approximately 50% to 65% in participants who received the four-day intervention. Reinhart noted that the research is still in its early stages. The technology also has limitations. “It’s an unfortunate fact of life that as we age we all become a little more forgetful,” Reinhart said. The findings are “quite remarkable,” said Dr.
Study could be used to help boost cognitive performance of people developing Alzheimer's disease.
[Purchase a Team or Enterprise subscription for per week You will be billed per month after the trial ends](https://enterprise.ft.com/en-gb/services/group-subscriptions/group-contact-us/b/?barrierName=anon_barrier&segmentId=9fbe4fe1-9315-3d67-cc6d-2bc7650c4aea&ft-content-uuid=d0efd576-8d11-4955-80b1-de29a335c63a) [Purchase a Print subscription for 11,12 € per week You will be billed 107,91 € per month after the trial ends](https://subs.ft.com/spa3_uk3m?segmentId=461cfe95-f454-6e0b-9f7b-0800950bef25&utm_us=JJIBAX&utm_eu=WWIBEAX&utm_ca=JJIBAZ&utm_as=FIBAZ&ft-content-uuid=d0efd576-8d11-4955-80b1-de29a335c63a) [Purchase a Digital subscription for 6,64 € per week You will be billed 39 € per month after the trial ends](https://subs.ft.com/spa3_digital?ft-content-uuid=d0efd576-8d11-4955-80b1-de29a335c63a)
Keeping a romantic relationship healthy takes work — and the burden doesn't just rest on women, according to a new U of A study of mixed-gender couples that ...
“If what is happening in your relationship is good, double down on that so you can reap those rewards into the future. “I think the expectation for women to serve as relationship managers has let men off the hook in some ways. Johnson’s work was funded by the “On the flip side, when things are not going well, men have just as much power as women in their relationship to figure out what’s happening, contain it, cope with it and try to prevent it from spilling over into how things go tomorrow.” But men have just as much responsibility for taking action and capitalizing on the good times when their partnership is going well, and building on it so they can continue to enjoy good times in the future for themselves and their partners. “It challenges the notion that women are these unique barometers who are more attuned to what’s happening, and that they have diagnostic abilities men just don’t have,” said Johnson, a professor in the
Robert Reinhart, an assistant professor at Boston University and a co-author of the study, said memory loss was a normal symptom of cognitive decline ...
Taking good care of your body and mind is taking good care of your brain.” Many people experience changes in their memory skills as they get older and it’s not necessarily a sign of dementia. “We watched the memory improvements accumulate over time with each passing day, so that the memory enhancement in short-term memory and long-term memory were observable at the one-month timepoint,” Reinhart said.
What if people with lived experience of spinal cord injury advised every stage and type of research about spinal cord injury? How would their perspective ...
NASCIC created the SCI Research Advocacy Course to meet those barriers head on. The Reeve Summit 2022 will be held in person for the first time in three years October 13-14 at CONVENE at 600 14th Street, NW, Washington, DC. Within the spinal cord community and across the spectrum of healthcare research, there’s a growing call for community-engaged research that integrates the voices of people with lived experience into research. Barry Munro, a quadriplegic who sustained a spinal cord injury in 1987 and has been an active advocate in SCI research ever since, will facilitate the workshop. “In medical conditions such as Parkinson’s disease and breast cancer, people living with the condition have partnered with research/clinical entities, industry, funders, and regulatory agencies. “Major SCI funders have grown to appreciate the community's role in research and require such engagement as part of their grant applications. Its expert authors concluded that “the clinical research field must embrace a paradigm shift that moves the balance of power from institutions and puts at the center the priorities, interests, and voices of the community.” The new NASCIC course, developed with the engagement practices it teaches, takes concrete steps toward that goal. Topics include access to healthcare, health equity, caregiving, research, emergency preparedness, and more over three general sessions and up to 18 focused breakout sessions. However, people with lived experience may be hesitant to serve as advisors because they feel they lack the knowledge needed to participate.” What will it take to get there? Where might we be today if that had always been the case? How would their perspective impact research, care, and policy-making?
International Space Station studies about wound healing and cardiology kicked off the week for the Expedition 67 crew following last week's departure of a ...
[undocked](https://blogs.nasa.gov/spacestation/2022/08/19/dragon-departs-station-to-return-scientific-cargo-to-earth/) from the [Harmony module](https://www.nasa.gov/mission_pages/station/structure/elements/harmony)’s forward port at 11:05 a.m. The quartet, including [Kjell Lindgren](https://www.nasa.gov/astronauts/biographies/kjell-n-lindgren/biography), [Bob Hines](https://www.nasa.gov/astronauts/biographies/bob-hines), and [Jessica Watkins](https://www.nasa.gov/astronauts/biographies/jessica-watkins), all from NASA, with [Samantha Cristoforetti](https://www.esa.int/Science_Exploration/Human_and_Robotic_Exploration/Commanding_role_for_ESA_astronaut_Samantha_Cristoforetti) of ESA (European Space Agency), worked throughout the day inside the [Kibo laboratory module](https://www.nasa.gov/mission_pages/station/structure/elements/japan-kibo-laboratory) conducting research operations in the [Life Science Glovebox](https://www.nasa.gov/mission_pages/station/research/experiments/explorer/Facility.html?#id=7676). [Oleg Artemyev](http://www.gctc.ru/main.php?id=158) and [Denis Matveev](http://www.gctc.ru/main.php?id=191) continued stowing spacewalking gear today after last week’s [spacewalk](https://blogs.nasa.gov/spacestation/2022/08/17/spacewalk-concludes-after-abnormal-battery-readings/) to outfit the European robotic arm for payload operations on the station’s Russian segment. [AstroPi](https://www.nasa.gov/mission_pages/station/research/experiments/explorer/Investigation.html?#id=7534) science computer in the [Harmony module](https://www.nasa.gov/mission_pages/station/structure/elements/harmony) where Cristoforetti would adjust its camera lens allowing European students to take night time photography of the Earth below. EDT and parachuted to a [splashdown](https://blogs.nasa.gov/spacestation/2022/08/20/dragon-splashes-down-with-scientific-cargo-for-analysis/) off the coast of Cape Canaveral, Florida, on Saturday at 2:53 p.m. [International Space Station](ihttps://www.nasa.gov/mission_pages/station/main/index.html) studies about wound healing and cardiology kicked off the week for the [Expedition 67](https://www.nasa.gov/mission_pages/station/expeditions/expedition67/index.html) crew following last week’s departure of a U.S. [heal wounds in microgravity](https://www.nasa.gov/mission_pages/station/research/experiments/explorer/Investigation.html?#id=8227). Hines checked fluids and plants growing for the [XROOTS botany study](https://www.nasa.gov/mission_pages/station/research/experiments/explorer/Investigation.html?#id=8088) that uses hydroponics and aeroponics techniques to promote space agriculture. A variety of other space research, spacesuit cleaning, and maintenance rounded out the day for the seven orbital residents. Roscosmos Flight Engineer [Sergey Korsakov](http://www.gctc.ru/main.php?id=1709) also participated in the heart research before he and Artemyev studied how to pilot spacecraft and maneuver robots on future planetary missions. The SpaceX Dragon resupply ship completed its cargo mission after 34 days attached to the space station on Friday.
UAB has pioneered use of social media to inform the public about an EFIC trial. Imagine you become a trauma patient. It can happen to anyone. You could get in a ...
For example, the TAP Trial will focus on whether a drug currently approved for use to reverse the effects of anticoagulants will be beneficial to a wider trauma population in stopping severe bleeding. UAB has since been the lead center on a number of multicenter EFIC trials and has created the ads and webpages for the other centers. The therapies that are used in trauma clinical trials are already well-vetted by the FDA and proven to work — in certain situations and populations. UAB has done that work, and put in hours and thousands of dollars to reach the community. [published his findings](https://pubmed.ncbi.nlm.nih.gov/26998781/) in 2016 and established UAB as a leader in this innovative type of community consultation. Compared to a previous in-person campaign, which cost $8,000 and reached 465 participants, the social media campaigns resulted in more than 1,000 webpage views for just $1,000 each. Opting out involves getting a wrist bracelet to wear in case the patient receives a trauma injury. Spending thousands of dollars to buy billboards and TV, radio and newspaper ads with no way to track exactly how many people had seen the information. Prior to that trial, which started in 2000, that specific patient population had not been the focus of research. The study could ultimately determine whether the intervention should become the standard of care for trauma patients like you, and thousands of lives could be saved. “We take very seriously our obligation to engage community members to get their feedback and input,” Stephens said. Researchers must show there is reasonable evidence the study has the potential to provide real and direct benefit to the patient.
Brock's Centre for Bone and Muscle Health marks 10 years of research, community impact - The Brock News, a news source for Brock University.
“The Centre is a reflection of how collective and collegial research leads to great new research initiatives and strong community connections,” she says. [Identifying a seating system](https://brocku.ca/brock-news/2014/10/brock-community-study-to-improve-wheelchairs-for-children-with-cerebral-palsy/)that would enable children and others in wheelchairs to avoid getting hot, sweaty and develop pressure sores — a study in partnership with Niagara Children’s Centre and Niagara Prosthetics and Orthotics. This unique equipment is in a lab of the Centre for Bone and Muscle Health. This event also provides students with the opportunity to present their work. [Children’s muscles](https://brocku.ca/brock-news/2021/04/bareket-falk-receives-brocks-award-for-distinguished-research-and-creative-activity/)are not as strong as adult muscles, even factoring into account children’s relatively small size compared to adults, but they can endure movement for a long time, perhaps even more than adults “We have a recognized centre housed in an academic institution that is a trusted resource for people seeking health knowledge,” he says.
Researchers have developed an AI tool that can analyze changes in breathing to detect and track the progression of Parkinson's disease.
“But you can align the instances in time and ask, what was the state of the EEG in those instances when the model decided that something was important for its decision? Many years of additional study will be needed to show the AI can reliably diagnose Parkinson’s at an earlier stage and track its progression, but Dorsey said this first study is a rare sign of progress. In aligning the data with information collected by an electroencephalogram (EEG), a device that measures brain activity, the researchers found that the model’s detection of Parkinson’s was associated with instances when the alpha and beta bands in the EEG signal were at high power. The information it provides about breathing is continuous, allowing the AI to analyze the entire inhale and exhale movement of the chest. Rather than requiring the use of clunky belts and tubes, it measures the reflections off a person’s body, allowing the AI to analyze a surprisingly rich trove of data about human physiology. It was trained on breathing data collected during 12,000 nights of sleep from institutions around the country, and tested on outside data.