Alzheimer's disease

2023 - 3 - 19

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Image courtesy of "desmoinesregister.com"

Opinion:Alzheimer's changed everything for my family, seemingly in ... (desmoinesregister.com)

Robert Brownell is a Polk County supervisor. I'm often asked why I got involved in politics. I'd like to say to bring justice to the land, and that's partly ...

Jenna would wake in the middle of the night and have bizarre episodes. She is getting terrific care, and I am grateful for that, too. I was isolating. By May, I was overwhelmed. 1 of 2022, I weighed 205 pounds. And I was right! I scoffed. I solve problems. Plan A was keeping Jenna in the home for as long as possible. Plan B was in-home care, and Plan C was long term care at a facility specializing in late-stage Alzheimer’s. For the Alzheimer’s person, it is not what that word means. There’s really no doubt about it.” He rambled on about the deterioration of brain cells in the hippocampus and frontal lobe, memory and mapping.

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Image courtesy of "Globalnews.ca"

More women develop Alzheimer's than men. This app wants to close ... (Globalnews.ca)

The app called BrainFit aims to help reduce people's risk of brain-ageing diseases like Alzheimer's, which disproportionately affect women.

But after starting to use this app, the first thing that I realized was that I wasn’t hitting the glasses that day that I thought I was. So that was an eye-opener for me,” Kelaidis said. Once downloaded, the app asks the user to rate themselves on a scale between one and five for habits like sleep, exercise, stress and nutrition. Other suggestions are more ambitious like taking tango lessons, learning a new instrument and starting volunteer work. So, it really means that diseases like Alzheimer’s are midlife diseases with symptoms that show up in old age.” Kelaidis explained that although she is only 46 years old, her goal in using the app is to “be a healthy mom” for her kids.

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Image courtesy of "The Medical Journal of Australia"

Assessing preparedness for Alzheimer disease‐modifying therapies ... (The Medical Journal of Australia)

In June 2021, the United States Food and Drug Administration (FDA) announced the accelerated approval of aducanumab for the treatment of Alzheimer disease.1 ...

Infusion therapies are now part of the armamentarium for the treatment of many other chronic diseases but increased ancillary staffing will be needed to manage the complexities of scheduling the biweekly infusions, the scans, and the complications arising. Therapeutic advancement is well underway, and the medical community needs to keep pace. Only 15% of Australian patients receive a diagnosis of dementia in a memory clinic, with most patients diagnosed in hospital settings. These are the first of many new dementia pathology‐specific DMTs. The treatment of multiple sclerosis in the past two decades has transformed care and prognosis, requiring considerable restructure to health care provision. Apolipoprotein E (APOE) genotypes are already known to have an impact on the safety and response to some anti‐amyloid monoclonal antibody treatments. APOE allele tests are not reimbursed in Australia and New Zealand, with some patients also concerned about the consequences of genetic testing for health or life insurance. New Medicare codes may need to be generated for the purposes of these treatments. Supportive care is the current gold standard of dementia medical treatment, including symptomatic treatments and non‐pharmacological therapies. [16](#16), [17](#17) Clinical phenotypes do not always match underlying molecular pathology in dementias, [18](#18) and obtaining a molecular diagnosis has been shown to definitively change management. Aducanumab was then limited to patients with early disease and the price was reduced. [8](#8) Are we ready for DMTs in Australasia?

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